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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized bone defectsto address the unmet need for bone augmentation and skeletal repair.Effective therapies for bone regeneration primarily require the coordinated combination of innovativeHowever, current techniques in bone tissue engineering have not yet reached valid translation into clinicalovercome these shortcomings and facilitate the clinical application of these techniques to enhance bone

Keywords： bone tissue engineering     stem cell     bone scaffold     growth factor     bone regeneration    

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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: Clinical imperatives for the reconstruction of jaw bone defects or resorbed alveolar ridge require newtherapies or procedures instead of autologous/allogeneic bone grafts.Regenerative medicine, based on stem cell science and tissue engineering technology, is considered asan ideal alternative strategy for bone regeneration.We propose comprehensive strategies based on stem cell and tissue engineering researches, allowing for

Keywords： bone regeneration     animal models     translational strategies     oral and maxillofacial region    

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Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: The review further exemplifies their applications for bone tissue regeneration.

Keywords： hybrid polymer     bone regeneration     tissue engineering     biomaterials    

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Tissue engineering of cartilage, tendon and bone

Hengyun SUN, Wei LIU, Guangdong ZHOU, Wenjie ZHANG, Lei CUI, Yilin CAO

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 61-69 doi: 10.1007/s11684-011-0122-1

Abstract:

Tissue engineering aims to produce a functional tissue replacement to repair defects.In our laboratory, we focus on construction of cartilage, tendon and bone.focusing on tissue regeneration and defect repair in our laboratory.Cranial and limb bone defects were also successfully regenerated and repaired in large animals.Based on sophisticated animal studies, several clinical trials of engineered bone have been launched

Keywords： Tissue engineering     cartilage     bone     tendon     recent advances    

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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Bone and teeth are hard tissues.Hard tissue diseases have a serious effect on human survival and quality of life.Furthermore, primary cilia act as sensors of external stimuli and regulate bone homeostasis.In this review, we summarize the roles of primary cilia in long bone development and remodeling fromIn addition, the cilium-related diseases of hard tissue and the manifestations of mutant cilia in the

Keywords： primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

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Effect of incorporating Elaeagnus angustifolia extract in PCL-PEG-PCL nanofibers for bone tissue engineering

Vahideh R. Hokmabad, Soodabeh Davaran, Marziyeh Aghazadeh, Effat Alizadeh, Roya Salehi, Ali Ramazani

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1,   Pages 108-119 doi: 10.1007/s11705-018-1742-7

Abstract: poly(ϵ-caprolactone) (PCL-PEG-PCL/EA) nanofibers and their potential applications for bonetissue engineering were studied.These results suggest that PCL-PEG-PCL/EA nanofibers might have potential applications for bone tissueengineering.

Keywords： Elaeagnus angustifolia     scaffold     electrospinning     human dental pulp stem cell     tissue engineering    

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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 470-483 doi: 10.1007/s11705-012-1217-1

Abstract: excellent osteoconductive, osteoinductive, biocompatible and biodegradable properties, and their high boneMacroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulatevascularized bone ingrowth and they enhance bonding between scaffolds and surrounding tissues.Engineering BG/biopolymers (BP) composites or hybrids may be a good way to prepare macroporous scaffoldsprogress in the past few years in preparing three-dimensional macroporous BG and BG/BP scaffolds for bone

Keywords： bioactive glass     biopolymer     bone regeneration     macroporous scaffolds     tissue engineering    

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The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 6-10 doi: 10.1007/s11684-007-0002-x

Abstract: Much has been considerably developed recently in the ophthalmic research of stem cell (SC) and tissueengineering (TE).

Keywords： available     observable     neuroregeneration     protection     function reconstruction    

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Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract: addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissueengineering has emerged, grown, and attracted increasing interest.Several important aspects related to tissue engineered nerves, including the theory on their constructionFurthermore, potential research directions for the future development of neural tissue engineering are

Keywords： nerve injury     tissue engineering     nerve grafts    

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Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(

Yang YU, Hong ZHANG, Hong SUN, Dandan XING, Fanglian YAO

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 388-400 doi: 10.1007/s11705-013-1355-0

Abstract: Therefore, the CS-g-PNIPAM/nHA composite is a potential biomaterial in bone tissue engineering.

Keywords： chitosan     poly(N-isopropylacrylamide)     hydroxyapatite     coil     globule     bone tissue engineering    

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Microorganism-derived biological macromolecules for tissue engineering

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 358-377 doi: 10.1007/s11684-021-0903-0

Abstract: materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissuereconstruction in tissue engineering and regenerative medicine.such as pullulan, alginate, dextran, curdlan, and hyaluronic acid, and their available sources for tissueengineering.

Keywords： biological macromolecules     regenerative medicine     tissue engineering     exopolysaccharide     carbohydrate    

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Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 1,   Pages 107-119 doi: 10.1007/s11465-018-0496-8

Abstract:

Tissue engineering (TE) is an integrated discipline that involves engineering and natural sciencesurgical treatments have been reported to have side effects on patients caused by organ necrosis and tissue

Keywords： tissue engineering     scaffolds     electrospinning     3D printing     molding techniques     conventional methods    

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Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 181-184 doi: 10.1007/s11684-007-0034-2

Abstract: to observe and visualize the changes in osteoblasts by electron microscopy during osteogenesis using tissueengineering technique.We also studied the feasibility of improving tissue vascularization of th

Keywords： feasibility     engineering     osteogenesis     vascularization     microscopy    

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Current progress on scaffolds of tissue engineering heart valves

DONG Nianguo, SHI Jiawei, CHEN Si, HONG Hao, HU Ping

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 229-234 doi: 10.1007/s11684-008-0043-9

Abstract: Tissue engineering heart valves (TEHV) may be the most promising valve substitute, but the study has

Keywords： function     scaffold     promising     research     engineering    

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Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissueengineering applications

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3,   Pages 339-347 doi: 10.1007/s11705-012-1209-1

Abstract: Dextran-hyaluronate (Dex-HA) based supermacroporous cryogel scaffolds for soft tissue engineering wereindicating the Dex-HA cryogel scaffold could be a promising porous biomaterial for applications in tissueengineering.

Keywords： cryogel scaffold     tissue engineering     dextran     hyaluronate     3T3-L1 preadipocyte    

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Title Author Date Type Operation

Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Journal Article

Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Journal Article

Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Journal Article

Tissue engineering of cartilage, tendon and bone

Hengyun SUN, Wei LIU, Guangdong ZHOU, Wenjie ZHANG, Lei CUI, Yilin CAO

Journal Article

Primary cilia in hard tissue development and diseases

Journal Article

Effect of incorporating Elaeagnus angustifolia extract in PCL-PEG-PCL nanofibers for bone tissue engineering

Vahideh R. Hokmabad, Soodabeh Davaran, Marziyeh Aghazadeh, Effat Alizadeh, Roya Salehi, Ali Ramazani

Journal Article

Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Journal Article

The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Journal Article

Progress and perspectives of neural tissue engineering

Xiaosong Gu

Journal Article

Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(

Yang YU, Hong ZHANG, Hong SUN, Dandan XING, Fanglian YAO

Journal Article

Microorganism-derived biological macromolecules for tissue engineering

Journal Article

Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Journal Article

Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Journal Article

Current progress on scaffolds of tissue engineering heart valves

DONG Nianguo, SHI Jiawei, CHEN Si, HONG Hao, HU Ping

Journal Article

Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissueengineering applications

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Journal Article